Plain-English Definitions

The Menopause & Perimenopause Glossary

Every term a doctor, a headline, or a search result might throw at you during this transition — defined simply, with a note on why some of them matter to your relationship, not just your body. Compiled by Vera and Theo so neither of you has to Google it mid-conversation. 62 terms and counting.

The Basics & Stages

The words for where someone is in the transition — because "menopause" isn't one moment, it's a years-long process with real stages.

Perimenopause

The transition leading up to menopause. Hormone levels rise and fall unevenly (not just decline), periods become irregular, and it typically lasts four to eight years, sometimes longer. Most of the symptoms people associate with "menopause" actually happen here.

Menopause

A single point in time: the moment twelve full months have passed since someone's last period. It isn't a phase you're "in" for years — it's a milestone you reach once, usually around age 51, though anywhere from the 40s to mid-50s is normal.

Postmenopause

Every year after menopause has been reached. Many of the acute symptoms (hot flashes, mood swings) tend to ease over time in postmenopause, while some longer-term health considerations, like bone and heart health, become more relevant.

Premenopause

The span of reproductive life before perimenopause begins — regular cycles, stable hormone patterns. Sometimes used loosely to mean "before menopause" in general.

Menopause transition

Another name for perimenopause — the two terms are used interchangeably in most medical literature.

Early menopause

Menopause that happens between ages 40 and 45, earlier than the typical range but not as early as premature menopause.

Premature menopause / Primary ovarian insufficiency (POI)

Menopause or ovarian shutdown occurring before age 40. It can happen for unknown reasons, from genetics or autoimmune conditions, or after certain medical treatments. It often carries a bigger emotional weight, since it arrives well outside the expected timeline.

Surgical menopause

Menopause caused by the surgical removal of both ovaries (a bilateral oophorectomy), often done alongside a hysterectomy. Unlike the gradual slide of natural perimenopause, hormone levels drop abruptly — sometimes within days — which can make symptoms hit harder and faster.

Induced menopause

Menopause brought on by a medical treatment — chemotherapy, radiation, or certain medications — rather than by surgery or the body's natural timeline.

Spontaneous (natural) menopause

Menopause that happens on its own, from the ovaries' natural decline, without surgery or medical treatment causing it.

Hormones, Explained

The chemical messengers behind most of what's changing — useful shorthand for conversations with a doctor, or with each other.

Estrogen

The primary female sex hormone, made mainly by the ovaries. It affects far more than the reproductive system — skin, bone, mood, temperature regulation, and the vaginal and urinary tissues all respond to it. Its erratic rise and fall during perimenopause, more than a steady decline, drives many symptoms.

Progesterone

A hormone released after ovulation that helps prepare and stabilize the uterine lining. Levels tend to drop earlier and more steeply than estrogen in perimenopause, which is one reason sleep and anxiety symptoms often show up before hot flashes do.

Testosterone

Usually thought of as a male hormone, but the ovaries and adrenal glands also produce smaller amounts in women, where it contributes to sex drive, energy, muscle mass, and mood. It declines gradually over decades, not just at menopause.

Follicle-stimulating hormone (FSH)

A hormone from the pituitary gland that tells the ovaries to develop an egg-containing follicle. As the ovaries respond less, FSH rises — a high FSH level is one (imperfect) marker doctors use to help gauge where someone is in the transition.

Luteinizing hormone (LH)

A pituitary hormone that triggers ovulation. Like FSH, it tends to rise as ovarian function declines.

Androgens

A family of hormones, including testosterone, that both sexes produce in different amounts. In women they support bone density, muscle mass, energy, and sexual desire.

DHEA (dehydroepiandrosterone)

A hormone made by the adrenal glands that the body can convert into small amounts of estrogen and testosterone. Levels naturally decline with age.

Progestin / progestogen

"Progestogen" is the umbrella term for anything — natural or synthetic — that acts like progesterone in the body. "Progestin" specifically refers to the synthetic versions used in birth control and some hormone therapies.

The Symptoms People Actually Notice

The day-to-day experiences — the ones that show up in a relationship long before anyone says the word "menopause" out loud.

Hot flash

A sudden wave of heat, often with a flushed face and sweating, that can last from thirty seconds to several minutes. It's caused by the brain's temperature-regulation center becoming more sensitive to small shifts in body heat as estrogen fluctuates.

Night sweats

Hot flashes that happen during sleep, often heavy enough to soak sheets or clothing. They're one of the most common causes of disrupted sleep during perimenopause — for both partners, not just the person having them.

Vasomotor symptoms (VMS)

The clinical umbrella term for hot flashes and night sweats — "vasomotor" refers to the blood-vessel changes that cause the sensation of heat.

Brain fog

Not a formal diagnosis, but a widely recognized cluster of perimenopausal symptoms: trouble concentrating, misplacing words, and short-term memory lapses. It's linked to hormonal shifts and, often just as much, to poor sleep.

Mood swings

Faster or more intense shifts in mood than someone is used to. Fluctuating (not just falling) estrogen and progesterone affect neurotransmitters tied to mood regulation, and disrupted sleep compounds the effect.

Perimenopausal anxiety

New or worsened anxiety — racing thoughts, a sense of dread, physical restlessness — that some people experience for the first time during perimenopause, even with no prior history of it.

Perimenopausal depression

A depressive episode occurring during the menopause transition. Research shows the risk of a first or recurring depressive episode measurably rises during perimenopause, likely tied to hormonal fluctuation layered on sleep loss and life stress.

Insomnia / sleep disturbance

Difficulty falling asleep, staying asleep, or waking too early. It's one of the most disruptive perimenopausal symptoms — and one of the biggest hidden drivers of irritability and conflict, since almost nothing affects patience like chronic poor sleep.

Formication

An unusual but real symptom some people describe during perimenopause: a tingling, itching, or "insects crawling on the skin" sensation, tied to hormonal changes affecting the nervous system.

Joint pain

Aching or stiffness in the joints, sometimes new to perimenopause, linked to estrogen's role in reducing inflammation and supporting joint tissue.

Low libido (reduced sexual desire)

A decrease in interest in sex. It has many overlapping causes during this transition — hormonal changes, vaginal dryness, sleep loss, mood, and simple relationship stress can all play a part, often at the same time.

Vaginal dryness

Reduced natural lubrication caused by declining estrogen, which thins and dries the vaginal tissue. It's extremely common and very treatable, but rarely discussed until it starts affecting intimacy.

Dyspareunia

The clinical term for pain during intercourse — often, though not always, a direct result of vaginal dryness and thinning tissue.

Heart palpitations

A sensation of a racing, pounding, or fluttering heartbeat. Usually benign and hormone-related during perimenopause, but new or severe palpitations should always be checked out by a doctor rather than assumed.

Irregular periods / menstrual cycle changes

Cycles that become shorter, longer, heavier, lighter, or unpredictable — often the very first sign that perimenopause has begun, sometimes years before any other symptom appears.

Premenstrual dysphoric disorder (PMDD)

A severe form of PMS involving significant mood disruption in the days before a period. For people with a PMDD history, perimenopause's hormonal swings can intensify these episodes before periods stop altogether.

Body & Long-Term Health

What lower estrogen means for the body over the years that follow menopause — the reason this isn't just a "symptoms that pass" story.

Genitourinary syndrome of menopause (GSM)

An umbrella term for the vaginal, vulvar, and urinary changes caused by declining estrogen — dryness, thinning tissue, and increased urinary urgency or infections. It's common, often under-discussed, and generally very treatable.

Vaginal atrophy

The thinning, drying, and loss of elasticity in vaginal tissue caused by lower estrogen — one specific piece of GSM (above).

Osteopenia

A measurable decrease in bone density that's lower than normal but not yet low enough to be classified as osteoporosis. It's often an early warning sign worth acting on.

Osteoporosis

A condition where bone density has dropped enough to make bones fragile and prone to fracture. Bone loss speeds up noticeably in the years right after menopause, as estrogen — which helps maintain bone — drops.

Bone mineral density (BMD) / DEXA scan

BMD is a measurement of how much mineral (mainly calcium) is packed into bone. A DEXA scan is the standard low-dose X-ray test used to measure it and assess fracture risk.

Cardiovascular disease risk

Estrogen offers some protective effect on the heart and blood vessels during reproductive years; that protection fades after menopause, which is part of why heart-disease risk rises for women in the postmenopausal years.

Metabolic syndrome

A cluster of conditions — increased waist size, higher blood pressure, higher blood sugar, and unhealthy cholesterol levels — that together raise the risk of heart disease and diabetes. Menopause-related shifts in fat distribution can make this cluster more likely.

Urinary incontinence

Involuntary leakage of urine. Thinning tissue and weaker pelvic floor muscles after menopause can make both stress incontinence (leaking when coughing or laughing) and urgency incontinence more common.

Urinary tract infection (UTI)

A bacterial infection of the urinary tract. Lower estrogen changes the vaginal and urinary environment in ways that make UTIs more frequent for some people after menopause.

Weight-bearing exercise

Any activity — walking, dancing, strength training — where bones and muscles work against gravity. It's one of the most effective, low-cost tools for protecting bone density during and after the menopause transition.

Treatment & Care Options

Words that come up once someone starts talking to a doctor — useful to recognize even before that conversation happens. Nothing here is medical advice; a doctor or menopause specialist is the right source for a personal treatment plan.

Hormone therapy (HT) / Hormone replacement therapy (HRT) / Menopause hormone therapy (MHT)

Three names for the same general treatment: replacing some of the estrogen (and often progesterone) the body has stopped making, to relieve symptoms like hot flashes and vaginal dryness. "MHT" is the term most current medical guidelines now prefer.

Estrogen therapy (ET)

Hormone therapy using estrogen alone, generally prescribed for people who no longer have a uterus (since estrogen alone can otherwise increase the risk of uterine lining overgrowth).

Systemic vs. local (vaginal) therapy

Systemic therapy (pills, patches, gels) circulates through the whole body and treats symptoms like hot flashes. Local vaginal therapy (creams, rings, tablets) treats vaginal and urinary symptoms directly, at a much lower dose, without significantly affecting the rest of the body.

Bioidentical hormones

Hormones that are chemically identical to the ones the human body produces. Some are government-approved and regulated; the term is also used to market unregulated custom-compounded products, so it's worth asking a provider which kind is being discussed.

Compounded hormones

Hormone preparations mixed by a pharmacy to a custom formula or dose, rather than using a standardized, government-approved product. They aren't held to the same regulatory testing standards, which is worth knowing before choosing between the two.

SERM (selective estrogen-receptor modulator)

A class of medication that acts like estrogen in some tissues and blocks its effects in others — used for some menopause symptoms and, in different forms, for osteoporosis or breast-cancer treatment.

SSRIs / SNRIs for hot flashes

A class of antidepressant medications that, at certain doses, are also government-approved or commonly prescribed off-label to reduce hot flashes and night sweats — a useful non-hormonal option for people who can't or don't want to take hormone therapy.

Gabapentin

A non-hormonal medication, originally developed for seizures and nerve pain, that's also used off-label to help with hot flashes and sleep disruption.

Vaginal estrogen

Low-dose estrogen delivered directly to the vaginal tissue via cream, ring, or tablet, to treat dryness and related symptoms with minimal effect on the rest of the body.

Vaginal moisturizers vs. lubricants

Moisturizers are used regularly to improve tissue hydration over time; lubricants are used in the moment to reduce friction during sex. Both are non-hormonal and available without a prescription.

Phytoestrogens / isoflavones

Plant-based compounds, found in foods like soy and red clover, that weakly mimic estrogen in the body. Evidence for how much they help with symptoms is mixed, and they're worth discussing with a doctor rather than assuming they're risk-free.

Kegel exercises

Exercises that strengthen the pelvic floor muscles, which can help with certain kinds of urinary incontinence and, for some people, sexual function.

Menopause Society Certified Practitioner

A healthcare provider who has passed a competency exam in menopause care through The Menopause Society (formerly NAMS) — a useful credential to look for when searching for a doctor who specializes in this transition.

Women's Health Initiative (WHI)

A major, long-running U.S. research study, launched in 1991, whose early findings on hormone therapy and health risk shaped (and, for years, discouraged) hormone therapy use. Later re-analysis softened some of its original conclusions, especially for people who start therapy earlier in the transition — a good example of why it's worth discussing current guidance with a doctor rather than decades-old headlines.

Words for the Partner's Side

This is a two-sided transition. A few terms for what's often happening on the other side of the bed at the same time.

Andropause / male hormone changes

Not a formally standardized medical diagnosis the way menopause is, but a widely used informal term for the gradual decline in testosterone some men experience with age — lower energy, mood changes, and reduced sex drive, on a much slower timeline than menopause.

Empty nest transition

The adjustment period as children grow up and leave home — a life stage that, for many couples, overlaps directly with perimenopause and adds its own layer of identity and relationship change.

Desire discrepancy

A general relationship term (not specific to menopause) for when partners have different levels of interest in sex at a given time. It becomes especially relevant during the menopause transition, when one partner's desire may shift while the other's hasn't.

Sandwich generation

A term for adults simultaneously supporting aging parents and their own children — a common source of added stress that frequently coincides with the menopause transition and can compound its effects on a relationship.

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Didn't find what you're looking for?

This glossary covers the terms people ask about most, but it isn't exhaustive — and it's educational, not medical advice. For anything specific to your own body or relationship, a doctor (ideally a Menopause Society Certified Practitioner) is the right source, or ask the Facilitator for help putting a question into words.

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